ABSTRACT
Objective To study the chemical from the roots of Rosa multiflora var. cathayensis. Methods The silica gel column chromatography was used to separate the chemical constituents from the roots of Rosa multiflora var. cathayensis. HPLC was used to analyze its purity, chemical and spectroscopy methods were used to determine their structures. Results Nine constituents were isolated and identified as multifloside A (1), arjunic acid (2), 1β-hydroxyeuscaphic acid (3), arjunetin (4), kaji-ichigoside F1 (5), euscaphic acid (6), tormentic acid (7), myrianthic acid (8), and rosamultin (9). Conclusion Compound 1 is a new compound named multifloside A; All compounds are obtained from the genus Rosa for the first time.
ABSTRACT
This study was designed to investigate triterpenoids from the roots of Rosa laevigata Michx. The silica gel column chromatography was used to separate the chemical constituents from the roots of Rosa laevigata Michx. HPLC was used to analyze its purity and chemical constitution. Spectroscopy methods were used to determine their structures. Five constituents were isolated and identified as19α-OH-3β-E-feruloyl corosolic acid (1), 23-hydroxy-tormentic acid (2), 2α, 3β, 19α, 23-tetrahydroxy-12-en-28-oleanolic acid (3), 2α, 3α, 20β-trihydroxyurs-13 (18)-en-28-oic-acid (4), 2α, 3β, 20β-trihydroxyurs-13 (18)-en-28-oic-acid (5). Compound 1 was assigned as a new compound, compounds 4, 5 were obtained from the genus Rosa for the first time.
ABSTRACT
<p><b>OBJECTIVE</b>To observe the ways of diagnosis and treatment of bilateral facial nerve palsy.</p><p><b>METHODS</b>Seven cases of bilateral facial nerve paralysis in 1996 - 2003 were retrospectively reviewed, and then the ways of diagnosis and therapies of these cases were analyzed. There were 6 patients with doubtless diagnosis. They were diagnosed as acute leukaemia, Vogt-Koyanagi-Harada disease (VKH), Machado-Jesoph disease, bilateral mandible fractures, Guillain-Barré syndrome, and Bell's palsy. The last one was diagnosed as Herpes zoster virus infection or Lyme disease. In all these cases, there were 4 of 5 positive cerebrospinal fluids test, 1 of 6 positive lyme antibody test, 2 of 5 positive images test, 7 of 7 EMG and Br test showed that the paralysis was peripheral palsy. All the 7 cases were treated with steroid and vitamin.</p><p><b>RESULTS</b>House-Brackmann I was defined as complete recovery, after up to 2 months follow up, there were four cases got completely recovery while 2 cases incomplete recovery, and 1 case was not reacted to the therapy.</p><p><b>CONCLUSIONS</b>Bilateral facial nerve paralysis was rare, and it was difficult to diagnosis and differentiation, while diagnostic mistakes would be serious. More attention should be paid to it in clinic.</p>